We are sensory biologists interested in identifying the genetic, molecular, and neuronal mechanisms by which animals sense and translate environmental cues such as chemicals and temperature into specific changes in behavior and development. Understanding the regulation of sensory signaling and signal processing is of significant biomedical importance since misregulation of these pathways leads to many neurological and behavioral disorders.
Munzareen Khan, Anna H. Hartmann, Michael P. O'Donnell, Madeline Piccione, Anjali Pandey, Pin-Hao Chao, Noelle D. Dwyer, Cornelia I. Bargmann, Piali Sengupta
Context-dependent reversal of odorant preference is driven by inversion of the response in a single sensory neuron type
Current research in our lab focuses on two major areas
using the powerful and elegant C. elegans model organism.